
When you think of dermal fillers, you might imagine instant results plumper cheeks, smoother skin, and softened lines. But what if you could achieve all that and stimulate your body’s own collagen to keep the results going naturally? That’s exactly what Ellansé offers.
Unlike traditional fillers that only add temporary volume, Ellansé works with your skin from within. It doesn’t just fill lines it helps rebuild structure, restore firmness, and rejuvenate your appearance over time.
In this guide, I’ll explain what Ellansé is used for, how it works, what makes it different from other fillers, and what you can expect before and after treatment.
What Is Ellansé?
Ellansé is a collagen-stimulating dermal filler designed to restore lost volume and improve skin quality gradually. It’s made from a unique ingredient called polycaprolactone (PCL) a biocompatible, biodegradable material that’s been safely used in medical implants for decades.
When injected into the skin, Ellansé immediately provides volume like a traditional filler. However, over the following months, it triggers your body’s natural collagen production, creating firmer, smoother, and more youthful-looking skin that lasts long after the initial gel is absorbed.
How Does Ellansé Work?
Ellansé works in two phases instant correction and long-term regeneration.
1. Immediate effect: The gel carrier provides instant volume and smooths out wrinkles or folds right after injection.
2. Collagen stimulation: As the gel gradually breaks down, it stimulates fibroblasts the cells responsible for collagen production. This new collagen then replaces the gel, maintaining volume naturally.
The result is skin that not only looks refreshed but actually is rejuvenated from within.
What Is Ellansé Used For?
Ellansé is one of the most versatile treatments available for facial and hand rejuvenation. Here are the most common uses:
1. Restoring Facial Volume
As you age, you naturally lose fat and bone structure in areas like the cheeks, temples, and jawline. This loss of support can make your face look tired or hollow.
Ellansé can restore this lost volume subtly and naturally, recreating youthful contours without the “overfilled” look sometimes associated with traditional fillers.
2. Smoothing Deep Lines and Wrinkles
Ellansé effectively softens nasolabial folds (smile lines), marionette lines, and other creases that deepen with age. Because it rebuilds collagen, results appear smooth and natural rather than stiff.
3. Lifting Sagging Skin
With collagen stimulation, the skin becomes firmer and more elastic over time. This provides a mild lifting effect, especially in the lower face and jawline.
4. Rejuvenating the Hands
Hands are one of the first areas to show signs of ageing with thinning skin, visible veins, and tendons. Ellansé adds back subtle volume while improving skin texture, making hands look younger and healthier.
5. Enhancing the Neck and Décolletage
Ellansé can also be used on the neck and chest to smooth fine lines, improve skin tone, and reduce the crepey texture that develops with sun exposure and ageing.
6. Non-Surgical Contouring
In experienced hands, Ellansé can be used to refine features such as enhancing cheekbones, defining the jawline, or improving facial symmetry all without surgery.
How Ellansé Differs from Traditional Fillers

Traditional dermal fillers, such as those made with hyaluronic acid (HA), work by adding temporary volume beneath the skin. These fillers are effective for smoothing wrinkles and enhancing facial contours, but the results typically last only about six to twelve months before the substance gradually dissolves.
Ellansé, however, takes a different approach. Instead of using hyaluronic acid, it’s made from polycaprolactone (PCL) a biocompatible material that not only adds volume immediately but also stimulates your skin’s natural collagen production. This means the results improve over time as your skin becomes firmer and more resilient.
In terms of longevity, Ellansé can last anywhere from one to four years, depending on the version used, making it one of the longest-lasting fillers available. While traditional HA fillers can be dissolved if needed, Ellansé cannot be reversed. However, it naturally fades as the body gradually breaks it down.
The key advantage of Ellansé lies in this combination of immediate enhancement and long-term skin regeneration offering results that look natural and last far beyond what most standard fillers can achieve.
Different Types of Ellansé
Ellansé comes in several formulations designed to last for different durations. They all deliver the same rejuvenating effect but vary in how long results are maintained:
– Ellansé-S: Lasts approximately 1 year.
– Ellansé-M: Lasts up to 2 years.
– Ellansé-L: Lasts up to 3 years.
– Ellansé-E: Lasts up to 4 years.
Your practitioner will recommend the best option depending on your goals and the treatment area.
Areas That Can Be Treated with Ellansé
Ellansé is suitable for multiple areas of the face and body:
– Cheeks and midface.
– Temples and forehead.
– Nasolabial folds and marionette lines.
– Chin and jawline.
– Neck and décolletage.
– Hands.
It’s not typically used for lips or tear troughs due to the delicate nature of those tissues.
Benefits of Ellansé

Here’s why both patients and practitioners love this collagen-stimulating filler:
1. Long-lasting results: Enjoy firmer, smoother skin for up to four years.
2. Natural appearance: Stimulates your body’s collagen rather than just adding artificial volume.
3. Customisable treatment: Different formulations allow tailored results.
4. Improved skin quality: Over time, skin becomes thicker, tighter, and more radiant.
5. Minimal maintenance: No need for frequent top-ups like other fillers.
What to Expect During Treatment
Your Ellansé treatment is quick and comfortable, usually taking 30–60 minutes. Here’s what typically happens:
1. Your practitioner will cleanse and mark the treatment area.
2. A numbing cream or local anaesthetic may be applied for comfort.
3. The filler is injected using a fine needle or cannula.
4. The area may be gently massaged to distribute the product evenly.
Most patients describe the procedure as mildly uncomfortable at most.
Aftercare and Recovery
You can usually return to your normal activities immediately after treatment, though you may notice mild redness, swelling, or tenderness at the injection site.
To help your skin recover smoothly:
– Avoid strenuous exercise for 24–48 hours.
– Keep away from saunas or excessive heat for a few days.
– Don’t massage or press the treated area unless advised.
– Avoid applying makeup for at least 12 hours.
– Any minor side effects usually settle within a few days.
When Will You See Results?

You’ll notice an immediate improvement right after treatment thanks to the gel component. However, the true magic of Ellansé develops over time.
Collagen stimulation begins within a few weeks, and the skin continues improving for 3–6 months. The results then last from 1 to 4 years, depending on the formulation used.
Is Ellansé Safe?
Yes Ellansé has an excellent safety record when administered by a qualified medical professional.
Its main ingredient, polycaprolactone, has been used safely in medical devices for over 20 years. The body naturally absorbs it as new collagen replaces the material.
As with any injectable, there are potential side effects such as swelling, redness, or bruising. Rare complications can include nodules or unevenness, which are minimised by proper technique and aftercare.
Always ensure your treatment is carried out by an experienced, medically trained practitioner in a clinical setting.
Who Is a Good Candidate for Ellansé?
You may be a great candidate if you want:
– Long-lasting, natural rejuvenation.
– To restore facial volume lost through ageing.
– Firmer, tighter, more youthful skin.
– A non-surgical solution to sagging or hollow areas.
However, 7 may not be suitable if you:
– Are pregnant or breastfeeding.
– Have an active infection or skin inflammation.
– Have a history of severe allergies.
– Prefer reversible fillers.
Your practitioner will assess your suitability during a detailed consultation before proceeding.
Comparing Ellansé to Other Fillers
Different dermal fillers offer different benefits, depending on your goals and the areas being treated. Hyaluronic acid (HA) fillers are the most common and provide instant volume to areas like the lips, cheeks, and under the eyes. They’re also reversible, which makes them a popular choice for first-time patients. However, their effects typically last only six to twelve months.
Sculptra works differently instead of adding immediate volume, it stimulates your skin to gradually produce more collagen. Results appear over time and can last for two to three years, making it ideal for restoring facial volume in areas such as the temples or cheeks.
Radiesse also encourages collagen production while giving instant volume and lift, particularly suited for the lower face and hands. The results generally last between twelve and eighteen months, offering both contouring and rejuvenation benefits.
Ellansé combines the best of both worlds. Like Radiesse and Sculptra, it stimulates collagen, but it also provides immediate correction similar to HA fillers. What sets it apart is its longevity results can last from one to four years depending on the version used and its powerful ability to boost the skin’s natural regeneration. This unique blend of instant results and long-term improvement makes Ellansé one of the most advanced options among modern dermal fillers.
What Makes Ellansé Different
Unlike temporary fillers, Ellansé works in harmony with your body. Instead of relying on an artificial substance for plumping, it encourages your skin to heal and strengthen itself naturally.
This dual benefit instant results plus long-term collagen production gives it a unique position between a filler and a regenerative treatment.
Combining Ellansé with Other Treatments
For enhanced results, Ellansé can be combined with other non-surgical treatments such as:
Botox®: For smoothing expression lines.
Laser skin resurfacing: To improve texture and tone.
Microneedling: To boost collagen even further.
Skin tightening treatments: For lifting sagging areas.
Your practitioner will design a treatment plan tailored to your goals and skin type.
Why Collagen Stimulation Matters
Collagen is the protein that keeps your skin plump, firm, and youthful. From your mid-20s onward, collagen production declines by about 1–2% per year, leading to sagging, wrinkles, and thinning skin.
By stimulating new collagen, Ellansé essentially turns back the clock on this process strengthening your skin’s foundation and maintaining long-term firmness.
Cost of Ellansé Treatments
The cost of Ellansé varies depending on the number of syringes used and the formulation chosen (S, M, L, or E). Prices typically range from £350 to £600 per syringe in the UK.
Because results last up to four years, Ellansé is often more cost-effective over time than other fillers that require frequent maintenance.
Why Choose LMA Clinic for Ellansé?
At LMA Clinic, Ellansé treatments are performed by experienced aesthetic specialists with a deep understanding of facial anatomy and balance. Each treatment plan is tailored to enhance your natural beauty while maintaining subtle, realistic results.
Our focus is always on safety, precision, and artistry ensuring you look refreshed, not overdone.
Frequently Asked Questions About Ellansé
1. How soon will I see results after my Ellansé treatment?
Most patients notice visible improvement immediately after the procedure. The gel component of Ellansé provides instant volume and smooths out wrinkles right away. However, the real transformation takes place gradually over the next few months. As your body begins producing new collagen, your skin becomes firmer, smoother, and more radiant. This process typically peaks between three to six months, giving you a natural rejuvenation that continues to enhance your appearance long after the initial session.
2. How long do Ellansé results last?
The longevity of Ellansé is one of its strongest advantages. Depending on the formulation used S, M, L, or E results can last anywhere from one to four years. The difference in duration comes from how long the polycaprolactone (PCL) microspheres remain active within the skin. Even after the material gradually dissolves, the collagen that has formed continues to support the skin’s structure, helping maintain firmness and youthful contours well beyond the lifespan of traditional fillers.
3. Is Ellansé safe?
Yes, Ellansé is considered a safe and biocompatible filler when performed by a qualified practitioner. Its main ingredient, PCL, has been used in medical applications such as sutures and implants for decades. The body recognises and safely breaks it down over time, leaving behind natural collagen in its place. Like all injectable treatments, there is a small risk of temporary redness, swelling, or bruising, but these effects usually subside within a few days. Choosing a medically trained expert significantly reduces the risk of complications and ensures the best possible outcome.
4. Can Ellansé be used with other aesthetic treatments?
Absolutely. Ellansé integrates beautifully with many non-surgical treatments to create a more comprehensive rejuvenation plan. It can be combined with Botox® to soften dynamic expression lines, with laser resurfacing to refine skin texture, or with microneedling to further enhance collagen stimulation. Many patients also pair Ellansé with skin tightening treatments for a more lifted appearance. The key is a customised approach your practitioner will assess your skin and goals to design a combination plan that delivers balanced, natural results.
5. Is Ellansé reversible like hyaluronic acid fillers?
Unlike hyaluronic acid (HA) fillers, Ellansé cannot be dissolved using an enzyme. However, it doesn’t remain permanently in the skin. The PCL microspheres naturally degrade over time as your body’s own collagen takes over to maintain the result. This gradual fading process ensures the transition looks smooth and natural, rather than abrupt. For patients seeking a filler that encourages long-term rejuvenation rather than short-term correction, this property is often seen as a positive advantage.
6. What does the treatment feel like?
Most patients describe Ellansé injections as mildly uncomfortable rather than painful. A topical numbing cream or local anaesthetic is usually applied before the treatment to ensure comfort. The practitioner may use a fine needle or a blunt cannula to deliver the filler precisely into the targeted areas. You may feel slight pressure or a gentle stinging sensation during injection, but this subsides quickly. After the procedure, any tenderness typically resolves within a couple of days, allowing you to return to normal activities almost immediately.
7. How should I care for my skin after Ellansé treatment?
After your session, your practitioner will provide specific aftercare advice to support healing. It’s important to avoid strenuous exercise, excessive heat, and alcohol for the first 24 to 48 hours, as these can increase swelling. You should also avoid touching or massaging the treated areas unless instructed to do so. Makeup should be avoided for at least 12 hours to reduce the risk of irritation. Mild redness or swelling can appear initially but tends to settle quickly. Keeping your skin clean, hydrated, and protected from the sun will help your results last longer and look even better.
8. Who is the ideal candidate for Ellansé?
Ellansé is best suited for individuals who want a natural-looking, long-lasting rejuvenation without surgery. It’s an excellent choice for those who have noticed loss of facial volume, sagging skin, or deepening folds around the mouth and jawline. Because it promotes collagen regeneration, it’s especially beneficial for patients who want their skin to become firmer and more resilient over time. However, Ellansé may not be recommended for pregnant or breastfeeding women, individuals with active skin infections, or those who prefer reversible fillers. A detailed consultation will help determine if Ellansé is right for you.
9. Are there any risks or side effects I should know about?
As with any injectable treatment, minor side effects can occur. These include temporary swelling, redness, tenderness, or slight bruising at the injection site. In rare cases, small nodules or unevenness can develop, but this risk is minimised when the procedure is performed by a skilled medical professional using proper technique. Serious complications are extremely uncommon. Overall, Ellansé’s long-standing medical safety record and use of biocompatible materials make it one of the most trusted collagen-stimulating fillers available today.
10. Why should I choose Ellansé over other fillers?
Ellansé stands apart because it delivers both immediate and progressive rejuvenation. Traditional fillers simply add temporary volume that fades within a year, whereas Ellansé works with your body to rebuild lost collagen creating results that look and feel completely natural. Its longevity, combined with the ability to improve skin quality from within, means fewer maintenance sessions and more consistent results over time. For anyone seeking a treatment that offers visible lift, improved firmness, and lasting radiance, Ellansé provides an innovative and scientifically backed solution that truly goes beyond the limits of conventional fillers.
Final Thought: Why Choose Ellansé for Natural, Long-Lasting Rejuvenation
Ellansé offers more than just instant enhancement it’s a regenerative treatment that works with your skin to restore what time has taken away. By stimulating your body’s own collagen production, it helps rebuild structure, firmness, and elasticity from within, delivering natural-looking rejuvenation that lasts for years rather than months. Whether you’re looking to smooth wrinkles, lift sagging skin, or restore youthful volume to your face, neck, or hands, Ellansé provides a subtle yet transformative result that evolves beautifully over time.
At the London Medical & Aesthetic Clinic, our experienced practitioners tailor every Ellansé treatment to suit your facial anatomy and long-term goals. Each session is performed with precision, ensuring your results remain balanced, harmonious, and naturally refreshed.
If you’re considering Ellansé treatment, you can contact us at the London Medical & Aesthetic Clinic to discuss your personalised plan and discover the most effective approach to restoring natural volume, stimulating collagen, and achieving long-lasting, youthful results.
References:
1. Angelo-Khattar, M. et al. (2022). ‘Objective Assessment of the Long-Term Volumizing Action of Polycaprolactone-Based Dermal Fillers’. Journal of Cosmetic Dermatology, 21(5), pp. 1234–1241. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC9805706/
2. Zhao, H. et al. (2022). ‘Efficacy and Safety of Polycaprolactone Gel in Treating Moderate-to-Severe Nasolabial Folds in Chinese Patients’. Journal of Cosmetic Dermatology, 21(6), pp. 1456–1463. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC10171959/
3. Park, J.W. et al. (2022). ‘A Randomized, Evaluator-Blinded, Matched-Pair Prospective Study to Compare the Safety and Efficacy of SF-01 and Ellansé-M® in the Treatment of Moderate-to-Severe Nasolabial Folds’. Dermatologic Surgery, 48(4), pp. 567–574. Available at: https://pubmed.ncbi.nlm.nih.gov/35419911/
4. Bae, B., Lee, G., Oh, S. and Hong, K. (2016) ‘Safety and Long-Term Efficacy of Forehead Contouring With a Polycaprolactone-Based Dermal Filler’, Dermatologic Surgery, 42(11), pp. 1256–1260. Available at: https://pubmed.ncbi.nlm.nih.gov/27557035/
5. Christen, M.-O. & Vercesi, F., 2020. Polycaprolactone: How a Well-Known and Futuristic Polymer Has Become an Innovative Collagen-Stimulator in Esthetics. Clinical, Cosmetic and Investigational Dermatology, 13, pp.31–48. Available at: https://pubmed.ncbi.nlm.nih.gov/32161484/