
If you’re considering CO₂ laser treatment, you’re probably excited about the possibility of smoother, brighter, and more rejuvenated skin. Whether your goal is to reduce wrinkles, soften acne scars, improve texture, or address sun damage, CO₂ laser resurfacing is one of the most powerful treatments available. But achieving those impressive results doesn’t start on the treatment day it starts well in advance.
Proper pre-treatment preparation plays a crucial role in how well your skin responds to the laser. When your skin is healthy, hydrated, and protected before the procedure, you’re far more likely to experience smoother healing, better collagen production, and more even results. Good preparation can also reduce the chances of common side effects such as redness, hyperpigmentation, or prolonged downtime.
In this guide, I’ll walk you through everything you need to know to get your skin ready for CO₂ laser resurfacing. From adjusting your skincare routine and strengthening your moisture barrier to managing sun exposure, reviewing medications, and understanding what to avoid, every step helps ensure a safer and more effective treatment. By the end, you’ll feel confident and fully prepared for your appointment knowing you’ve given your skin the best possible start for a smooth, successful recovery and long-lasting results.
Understanding CO₂ Laser Treatment
Before diving into preparation, it helps to understand what CO₂ laser treatment actually does. CO₂ lasers use concentrated light energy to remove the outer layers of damaged skin. This process stimulates collagen production and encourages your skin to regenerate, leading to smoother, firmer, and more youthful skin over time.
Because the procedure is quite powerful, your skin needs to be in optimal condition beforehand. This not only helps achieve the best results but also reduces the likelihood of side effects, such as prolonged redness, irritation, or pigmentation changes.
If you’re planning this treatment, it’s best to consult with a CO2 laser clinic in London, where specialists can evaluate your skin type and guide you on preparation and post-care.
Stop Using Retinoids Ahead of Treatment
One of the most important steps in preparing for CO₂ laser resurfacing is adjusting your use of active skincare ingredients, especially retinoids.
Why pause retinoids:
Retinoids, including tretinoin and retinol, speed up skin cell turnover. While this is excellent for anti-ageing in daily skincare, it can make your skin more sensitive and prone to irritation during laser treatment. What to do:
– Stop using retinoids at least two weeks before your CO₂ laser session.
– If you’re on prescription-strength retinoids, consult your dermatologist for personalised timing.
– During this pause, focus on gentle, hydrating skincare to maintain skin health.
This step ensures your skin isn’t overly sensitive, which reduces the risk of post-treatment complications and allows for smoother healing.
Protect Your Skin from the Sun

Sun exposure is one of the most important factors to control before CO₂ laser treatment. UV rays can trigger inflammation, weaken the skin barrier, and increase your risk of developing post-treatment pigmentation issues such as dark spots or uneven healing. Because CO₂ laser resurfacing already places controlled stress on the skin, you want your skin to be in its healthiest, most stable condition beforehand.
Key preparation tips:
Avoid sunbathing and tanning beds for at least 4 weeks before treatment. Any recent tan natural or artificial makes the skin more reactive and can increase the likelihood of burns or pigmentation changes.
Use a broad-spectrum SPF 30–50 sunscreen daily. Apply it generously every morning and reapply every 2–3 hours if you’re outdoors. Don’t forget commonly missed areas like your neck, chest, ears, and hands.
Wear protective clothing and accessories. Wide-brimmed hats, sunglasses, and UPF-rated clothing offer an extra layer of defence, especially during peak sunlight hours.
Seek shade whenever possible. Even brief unprotected exposure can add unnecessary stress to the skin before your treatment.
Minimising UV exposure in the weeks leading up to your appointment gives your skin the best chance to heal evenly and respond effectively to the laser. Even a mild sunburn, tanning, or redness may force your clinician to delay the procedure for safety reasons so consistency and caution during this period are absolutely essential.
Stop Certain Skincare Products
In addition to retinoids, other products can make your skin more reactive to laser resurfacing. Products to pause:
– Exfoliating acids: Alpha-hydroxy acids (AHAs) and beta-hydroxy acids (BHAs) should be stopped 1–2 weeks prior.
– Vitamin C serums: Potent vitamin C formulations can increase sensitivity; pause 3–5 days before treatment.
– Other active ingredients: Products containing benzoyl peroxide or strong antioxidants may irritate skin if not paused.
The goal is to reduce any potential irritation so your skin can respond predictably to the laser.
Maintain Hydration
Hydrated skin is healthier, more resilient, and better able to heal after CO₂ laser resurfacing. Hydration tips:
– Drink plenty of water in the weeks leading up to your treatment.
– Use gentle, hydrating moisturisers with ingredients like hyaluronic acid or ceramides.
– Avoid overly heavy or occlusive products that could clog pores or interfere with healing.
From my experience, patients who prioritise hydration often experience less redness and faster recovery. Well-hydrated skin is better able to tolerate the laser and produce new collagen efficiently.
Address Skin Conditions Before Treatment
If you have any active skin conditions, such as eczema, rosacea, or acne flare-ups, it’s crucial to manage these before your CO₂ laser session. Why this matters:
– Inflamed or irritated skin is more likely to react negatively to laser resurfacing.
– Treatments on compromised skin can result in uneven healing or pigment changes.
Preparation tips:
– Consult your dermatologist about stabilising conditions at least 4 weeks before treatment.
– Avoid waxing, chemical peels, or other aggressive procedures in the month leading up to your session.
By addressing these issues ahead of time, you’re giving yourself the best possible outcome.
Schedule Around Your Lifestyle

CO₂ laser recovery requires some planning. Redness, peeling, and sensitivity are common in the first 7–14 days.
Tips for timing:
– Plan your appointment when you can take a week or two off social or professional commitments if needed.
– Avoid major events immediately after your treatment.
– Make arrangements for aftercare supplies, such as gentle cleansers, moisturisers, and sun protection.
Proper scheduling reduces stress and allows you to focus on healing, which ultimately improves your results.
Consider Pre-Treatment Topical Medications
Some clinics recommend pre-treatment topical medications to optimise healing.Examples include:
– Antiviral creams: If you’re prone to cold sores, applying antiviral medication can prevent flare-ups triggered by laser treatment.
– Barrier creams or ointments: These can strengthen the skin’s natural barrier and reduce sensitivity.
Your clinician at a CO2 laser clinic in London can advise whether these measures are appropriate for your skin type and history.
Plan for Post-Treatment Care
Preparing your skin before CO₂ laser treatment isn’t just about what you do in the weeks before it’s also about being ready for proper aftercare.
Key items to have on hand:
– Gentle cleanser and moisturiser recommended by your clinic.
– Broad-spectrum SPF 50+ sunscreen for weeks after treatment.
– Any prescribed ointments to protect or soothe the treated skin.
Knowing what you’ll need ahead of time ensures a smoother, more comfortable recovery.
Adjust Medications if Needed
Certain medications can affect how your skin heals.Examples include:
– Blood thinners: These can increase bruising; discuss with your doctor before treatment
– Isotretinoin (Accutane): Usually paused 6–12 months before CO₂ laser due to potential healing complications.
– Immunosuppressants: Can affect recovery; a dermatologist should provide guidance.
Being upfront with your clinician about medications ensures the safest experience and reduces complications.
Psychological Preparation
CO₂ laser is a transformative treatment, but it can be intense. Preparing mentally helps you approach the procedure with confidence. Tips:
– Understand the recovery timeline and set realistic expectations.
– Accept that peeling, redness, and temporary sensitivity are normal.
– Visualise the final results and focus on the long-term benefits.
A confident mindset can make the recovery period feel less stressful and more manageable.
Choosing the Right Clinic
Selecting an experienced clinic is as important as preparing your skin. Expertise, technology, and personalised care make a significant difference in results.
– Look for clinics with experienced laser specialists.
– Check that CO₂ lasers are clinically approved and well-maintained.
– Consider a CO2 laser clinic in London that offers comprehensive pre- and post-treatment guidance.
I’ve seen firsthand that patients who invest in a reputable clinic not only achieve better outcomes but also experience safer, smoother recoveries.
Summary Checklist for CO₂ Laser Preparation

Here’s a practical checklist you can follow:
– Stop retinoids 2+ weeks prior.
– Pause exfoliating acids and other strong actives.
– Avoid sun exposure and use SPF daily.
– Hydrate skin and body adequately.
– Treat active skin conditions beforehand.
– Schedule treatment when you have recovery time.
– Have aftercare products ready.
– Discuss medications with your clinician.
– Consult an experienced CO2 laser clinic in London.
Following this checklist helps ensure your skin is in optimal condition for treatment and recovery.
FAQs:
1. When should I schedule my CO₂ laser treatment?
It’s best to schedule your treatment when you have at least a week or two for recovery. CO₂ laser resurfacing often involves redness, peeling, and sensitivity in the first 7–14 days. Planning around your personal and professional commitments ensures you can focus on healing. Avoid major events immediately after treatment. This helps you maximise results and reduces stress during recovery.
2. What aftercare products do I need to have ready?
Before your treatment, stock up on gentle cleansers, moisturisers, and broad-spectrum SPF 50+ sunscreen. Any prescribed ointments or barrier creams recommended by your clinic should also be ready. Having these products ensures you can immediately follow post-treatment care. Proper aftercare promotes faster healing and reduces the risk of complications. Being prepared in advance supports smoother recovery.
3. How do medications affect CO₂ laser recovery?
Certain medications, like blood thinners, isotretinoin, or immunosuppressants, can impact how your skin heals. Discuss all medications with your clinician before the procedure. This ensures your treatment is safe and reduces the risk of bruising or delayed recovery. Adjusting or pausing specific medications may be recommended. Your doctor will guide you on the safest approach.
4. Why should I stop using retinoids before treatment?
Retinoids speed up skin cell turnover, which can make your skin sensitive to laser treatment. Stopping them at least two weeks beforehand reduces irritation and allows for smoother healing. Prescription-strength retinoids may require personalised timing adjustments. During this period, use gentle, hydrating skincare. This step helps your skin tolerate the laser better.
5. How important is sun protection before CO₂ laser?
Sun exposure increases the risk of pigmentation issues and can weaken your skin. Avoid tanning beds and sunbathing for at least four weeks before treatment. Use broad-spectrum SPF 30–50 sunscreen daily and protective clothing. Minimising UV exposure ensures even healing and optimal results. Even minor sunburn can delay your procedure.
6. Should I pause other active skincare products?
Yes, products like AHAs, BHAs, vitamin C serums, benzoyl peroxide, or strong antioxidants can increase skin sensitivity. Pause these at least a few days to two weeks prior, depending on the product. This reduces irritation during and after treatment. Focus on gentle, hydrating products instead. Proper preparation ensures predictable and safe results.
7. How can hydration improve results?
Hydrated skin heals faster, tolerates the laser better, and supports collagen production. Drink plenty of water in the weeks leading up to treatment. Use moisturisers with hyaluronic acid or ceramides for optimal skin hydration. Avoid heavy, pore-clogging products that may interfere with recovery. Well-hydrated skin reduces redness and accelerates healing.
8. Do I need to address skin conditions first?
Active skin issues like eczema, acne, or rosacea should be stabilised before CO₂ laser. Inflamed or irritated skin is more likely to react negatively to treatment. Consult your dermatologist at least four weeks in advance. Avoid other aggressive procedures during this time. Treating skin conditions beforehand ensures safer, more even results.
9. Should I prepare psychologically for CO₂ laser?
Yes, mental preparation helps you approach recovery confidently. Understand that peeling, redness, and sensitivity are normal post-treatment. Set realistic expectations for results and recovery time. Visualise the long-term benefits to reduce stress. A confident mindset can make the healing process smoother and more manageable.
10. How do I choose the right clinic?
Select a clinic with experienced CO₂ laser specialists and clinically approved equipment. Look for comprehensive pre- and post-treatment guidance. A reputable CO₂ laser clinic in London ensures safer, more effective results. Patient support and personalised care make a significant difference. Investing in the right clinic improves outcomes and recovery quality.
Final Thoughts: Final Thoughts: Preparing for Your Best Results
Preparing your skin properly before CO₂ laser treatment is essential for achieving safe, effective, and long-lasting results. By pausing retinoids and other actives, protecting your skin from the sun, maintaining hydration, and addressing any underlying conditions, you set the stage for a smoother treatment and faster recovery. Timing, planning, and selecting the right clinic such as a reputable CO₂ laser clinic in London also play a major role in the outcome.
When done correctly, CO₂ laser resurfacing can transform your skin, reduce wrinkles, minimise scars, and restore a youthful glow. Approach it with care, follow your clinician’s guidance, and you’ll maximise both your results and your confidence throughout the process. If you’re considering CO2 laser clinic in London, you can contact us at the London Medical & Aesthetic Clinic to discuss your personalised body-contouring plan and discover how this innovative technology can help you sculpt, tone, and define your physique safely and effectively.
Reference:
1. Rajput, C.D., Gore, S.B., Ansari, M.K. et al. (2021) ‘A Prospective, Nonrandomized, Open-label Study Comparing the Efficacy, Safety and Tolerability of Fractional CO₂ Laser Versus Fractional Microneedling Radiofrequency in Acne Scars’, Journal of Cutaneous and Aesthetic Surgery, (2021). https://pmc.ncbi.nlm.nih.gov/articles/PMC8423204/
2. Pooja, T. (2020) ‘A Randomized Study to Evaluate the Efficacy of Fractional CO₂ Laser Resurfacing versus Microneedling and PRP in Post-Acne Scarring’, Indian Dermatology Online Journal, (2020). https://pubmed.ncbi.nlm.nih.gov/32695692/
3. Sriram, R., Chandrashekar, B.S., Gowda, H.H. & Madura, C. (2024) ‘Comparative study in treatment of acne scars: Fractional CO₂ laser versus Microneedling Fractional Radiofrequency’, Journal of Cutaneous and Aesthetic Surgery, 17, pp. 214–218. PMC11494830. https://pmc.ncbi.nlm.nih.gov/articles/PMC11494830/
4. Grezy, R. et al. (2023) The Use of a Fractional Laser in Acne Scar Treatment A Systematic Review, Life, 15(6), 915. https://www.mdpi.com/2075-1729/15/6/915\
5. A Randomized Study to Evaluate the Efficacy of Fractional CO₂ Laser, Microneedling and Platelet‑Rich Plasma in Post‑Acne Scarring (2020), Indian Dermatology Online Journal. https://pubmed.ncbi.nlm.nih.gov/32695692




