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Collagen Stimulation

We pride ourselves in being the leading clinic in Collagen Stimulation treatment in the UK and Europe. Dr Ayham Al-Ayoubi is a leading Collagen Stimulation Training Surgeon and he is an internationally recognized expert in the procedure with more than 7,000 cases of Collagen Stimulation treatments performed at our clinic.

Collagen Stimulation is a long lasting, clinically-proven, non-invasive, stimulating injectable treatment that is designed to smooth out and soften lines and wrinkles, restore facial volume and contour the face in a natural way.

Collagen Stimulation works differently from traditional dermal fillers. It’s a unique collagen replenishing treatment that helps to gradually and subtly reduce lines, wrinkles and folds. By helping to replenish the body’s own facial collagen and restore lost volume, it can give a fuller, more natural look that can last for up to 3-5 years.

Collagen Stimulation Use

It is considered to be a discreet approach to achieving a fresher, younger-looking appearance, probably used by many Hollywood stars who deny having surgery but look to have defied age and remain still naturally good looking without a “done” plastic appearance.

Poly-L-lactic acid, the main ingredient of Collagen Stimulation has been used successfully in surgical procedures for more than 50 years, among others for bioresorbable sutures, in bone plates and screws, and as a medium for medication.

There are four main indications where Collagen Stimulation can be used:

  1. Collagen Stimulation for Facial Volumization
  2. Collagen Stimulation for Scar Treatment
  3. Collagen Stimulation for Facial Asymmetry

It can be used for loss of fat and soft tissue in the face, premature ageing of the face, hollow cheeks and temples, nose to mouth folds, deep folds and wrinkles, marionette lines, sagging jowls, wrinkly chest / decolletage, wrinkly hands, deep acne and traumatic scarring.

Collagen Stimulation is used on most parts of the face (except on the forehead and above the lips). Common areas of use include cheeks, temples, inframalar region, chin, prejowl sulcus, and marionette lines.

More advanced areas include infraorbital regions and lateral brow. Creative uses have been reported in the treatment of acne, deep acne scarring and varicella scars, chest wall, prominent facial asymmetry and the dorsum of the hands

Collagen Stimulation is ideal to be used for deep tissue filling or in the dermal subcuta-neous junction to smooth out and soften lines and wrinkles, restore facial volume, contour the face in a natural way. It is not meant to be injected intra-dermally.

As it differs from traditional, static dermal fillers such as hyaluronic acid and collagen, as a stimulatory product it causes the growth of fibrous tissue or collagen within the body, which then results in volume restoration gradually.

Collagen Stimulation Aesthetic works within the deep dermis, the skin’s structure is reinforced as Collagen Stimulation Aesthetic helps to replace lost collagen. This reinforced collagen structure provides a foundation that gradually restores the look of fullness of shallow to deep facial wrinkles and folds that have been depleted over time.

The results of Collagen Stimulation Aesthetic are different because Collagen Stimulation gradually and subtly corrects these facial wrinkles. This can provide a refined, more youthful looking appearance that can last from three – five years.

Collagen Stimulation can be used for Scars, Facial Asymmetry and  Aging Hands, neverthless, It requires a special understanding of how it works, where it can be used, and how it should be injected.

Collagen Stimulation Suitability

Collagen Stimulation is suitable for both women and men of different ages and it can help with deep folds around the mouth and nose, sunken cheeks, facial scars, deep acne scars and loose skin.

In the 20s: Collagen production slows down and then becomes dormant.
This is an ideal time to start Collagen Stimulation to keep the collagen reserves active and for skin tightening.
In the 30s/ 40s: Collagen Stimulation is ideal for long lasting lines and wrinkle correction

It enhances cheek volume and stimulates collagen in a natural way.

In the 50s and onward: Collagen Stimulation is ideal to restore facial contours and volume and correct facial laxity and improve the jaw line and other areas.
Patients can achieve full face lifting without the need for aggressive surgery with the results lasting up to 5 years.


A review at our clinic has shown that the improvements obtained with Collagen Stimulation have lasted for up to 2-4 years. Treatment usually consists of 2 to 4 sessions lasting up to half an hour; usually2-3 weeks apart with no ‘downtime’.

How does Collagen Stimulation work?

With time our skin loses its full, firm, youthful appearance and becomes thinner and starts to wrinkle and fat tissue, which also helps to fill out our faces, is lost, causing skin to sag and wrinkle further. For some people, the loss of fat tissue and the reduction in skin volume can make their face look thin and narrow and due to this look tired and appear older than they actually are.

Collagen Stimulation is a biocompatible, resorbable injectable product composed of poly-L-lactic acid (PLLA).  It falls in the class of a stimulatory product that creates its effect through encouraging neocollagenesis when injected. Collagen Stimulation is a synthetic polymer from the a-hydroxyl-acid family that is similar to absorbable suture material.

Collagen Stimulation Aesthetic works to replace lost collagen in a series of treatments administered by Dr Ayham Al-Ayoubi himself at our clinic. On average, two – four injection sessions are needed over a period of 2-8 weeks gap between each session. The number of injection sessions and the number of injections per session vary from person to person.

Collagen Stimulation treats most areas of the face that may have deeper lines, wrinkles and folds or loss of soft tissue, fat and hollow arees. The results can show immediatley, however, it will take  approximately 2 – 4 weeks to see the significant improvment (however, in some patients this may take longer or require more treatments).

Unlike surgical options, Collagen Stimulation can provide gradual, natural-looking results through less traumatic treatment. Patients can achieve a full face lifting effect which usually lasts up to 2 – 4 years.

Collagen Stimulation in particular requires this education because it is administered in usually three or more sessions covering a 3 month period or more with ultimate results achieved over a 4 – 6month time frame. Patients who not willing or able to wait for improvement may need additional augmentation with a hyaluronic acid to tide them over in the mean time.

Because of the volume of the water in the suspension, patients will leave the office looking filled; however, they should be aware that the improvement they see immediately will be gone in 2 to 4 days and they will then await the collagen growth that can be seen starting at 2 to 4 weeks. Patients should also be cautioned to prepare for the possibility of bruising and avoid non-steroidal anti-inflammatory medications prior to an injection.<br>

Collagen Stimulation Safety

The science behind Collagen Stimulation involves more than 50 years of use in human medical applications. From absorbable sutures to resorbable screws, it has proven to be biocompatible, well tolerated, and effective.

Collagen Stimulation is officially approved by MHRA in the UK and the FDA in the USA and for restoration and/or correction of the signs of facial fat loss (lipoatrophy) and is used for treating facial lines and wrinkles.

Immediate side effects may include injection-related events at the site of injection, such as minimum redness, slight tenderness or discomfort, some bruising and rarely swelling. All of these immediate side effects usually last only five- seven days.

A delayed appearance of small bumps under the skin in the treated area could rarely occur. Generally these bumps are not visible and may only be noticed when pressing on the treated area. This rare side effect is usually an effect of the product being injected too superficially causing a lump of product or collagen to form, but vigorous massage usually prevents this.

Advanced Collagen Stimulation By Dr Ayoubi

Dr Ayham Al-Ayoubi has invented and developed his own advanced Collagen Stimulation techniques including Collagen Stimulation for treating facial asymmetry, deep acne scars, traumatic scarring, Double V and Tear Duct technique which has now been adopted by numerous plastic surgeons and cosmetic doctors worldwide.

Patients travel from all over the UK and from around the world to have Dr Ayham Al-Ayoubi perform Collagen Stimulation treatment at the London Medical and Aesthetic Clinic, which is one of the leading training centres for Collagen Stimulation treatment in the UK and Europe.

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