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What Is JUVÉDERM Injectable Gel?

As we age, our skin changes. Over time, the natural volume of youthful skin begins to diminish as wrinkles and folds form. But, with JUVÉDERM injectable gel, you don't have to just sit back and let it happen!

JUVÉDERM is a smooth consistency gel made of hyaluronic acid—a naturally occurring substance in your skin that helps to add volume and hydration. Your healthcare professional eases JUVÉDERM injectable gel under the skin to instantly restore your skin's volume and smooth away facial wrinkles and folds, like your “smile lines” or “parentheses” (nasolabial folds—the creases that run from the bottom of your nose to the corners of your mouth).

JUVÉDERM provides a smooth, natural look and feel—so everyone will notice (but no one will know)! In fact, studies show superior results of JUVÉDERM compared to a collagen-based dermal filler.†

  • Almost 90% of all study volunteers who were treated with both JUVÉDERM injectable gel and another dermal filler† preferred JUVÉDERM!
  • JUVÉDERM injectable gel is the first FDA-approved hyaluronic acid dermal filler that is proven to be safe and effective for persons of color.

Immediate Results

With JUVÉDERM the injection process takes only about 15 minutes and results are immediate. Plus, there's minimal recovery or downtime. So you can step into your doctor's office for treatment and step right back into your life.

JUVÉDERM is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

Benefits of JUVÉDERM Injectable Gel

Hyaluronic acid dermal fillers like JUVÉDERM injectable gel offer a safe and effective nonsurgical option for smoothing facial wrinkles and folds. In fact, they are the fastest growing nonsurgical aesthetic procedure in the United States according to the American Society of Aesthetic Plastic Surgery.1 But all dermal fillers are not the same!

Choosing JUVÉDERM injectable gel makes a difference:

  • JUVÉDERM is the ONLY hyaluronic acid (HA) filler FDA approved* to last up to 1 year. Our unique manufacturing process provides a high concentration of cross-linked hyaluronic acid for long-lasting results. It also creates a smooth consistency gel that flows easily into the skin and provides a smooth, natural look and feel—so everyone willl notice (but no one will know)! Only JUVÉDERM is so smooth—other hyaluronic acid fillers currently on the market are made of granular consistency gels.
  • A "next-generation" filler: JUVÉDERM is a “next-generation” non-animal dermal filler that is made from hyaluronic acid—a naturally occurring substance that plays a vital role in hydrating your skin and replenishing its natural volume. No allergy skin tests are needed prior to receiving treatment.
  • Proven safety and effectiveness: JUVÉDERM injectable gel is the first FDA-approved hyaluronic acid dermal filler proven safe and effective in persons of color.
  • Quick and easy procedure: JUVÉDERM injectable gel is a nonsurgical physician-administered treatment that requires no allergy skin test and minimal recovery or downtime.
  • Personalized treatment: JUVÉDERM injectable gel is available in two formulations— JUVÉDERM Ultra for versatility in contouring and volumizing facial wrinkles and folds, and JUVÉDERM Ultra Plus, a more robust formulation for volumizing and correcting deeper folds and wrinkles. This allows your healthcare professional to tailor treatment to meet your unique needs.

JUVÉDERM is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

Important JUVÉDERM Treatment Considerations

JUVÉDERM Ultra and JUVÉDERM Ultra Plus are indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds). Side effects were usually mild to moderate lasting 7 days or less and included temporary injection site reactions like redness, pain, firmness, swelling and bumps.

How JUVÉDERM Works

JUVÉDERM injectable gel dermal filler is a nonsurgical, physician-administered treatment. Your healthcare professional eases JUVÉDERM under the skin using a fine needle to augment, or fill, the soft tissue of the dermis—the dense inner layer of skin beneath the epidermis—to add volume and diminish wrinkles and folds. JUVÉDERM injectable gel is great for your "laugh lines," "smile lines" or "parentheses" (nasolabial folds), or "marionette lines" (oral commissures).

JUVÉDERM is a "next-generation" filler. It is made from hyaluronic acid—a naturally occurring substance in your skin that helps to hydrate and add volume. Hyaluronic acid may diminish with age, contributing to the formation of wrinkles and folds. JUVÉDERM injectable gel works to correct this by restoring hyaluronic acid in your skin, helping to smooth wrinkles and folds.

What to Expect During Treatment

Because JUVÉDERM injectable gel is a simple, nonsurgical wrinkle treatment, there is minimal recovery or downtime. So you can make an appointment to stop by your healthcare professional's office for treatment on the way home from work or the gym, or even while the kids are at soccer practice—and get right back to your life. Here's what to expect when you visit your healthcare professional's office for treatment. (Please note that although this experience is typical, the routine at your healthcare professional's office may be different.)

Before you go: Some doctors recommend that you avoid any medications that can prolong bleeding, such as aspirin and non-steroidal anti-inflammatories (NSAIDs), for at least a week prior to treatment in order to reduce the risk of bruising and bleeding at the injection site. Ask your healthcare professional what he or she recommends.

When you arrive: If this is your first visit, your healthcare professional will ask about your medical history, including any allergies you may have or medications you may take, and will tell you more about wrinkle treatment with JUVÉDERM. JUVÉDERM injectable gel does not require an allergy test.

Determining your treatment needs: Your healthcare professional will examine the soft tissue of your face to assess the depth of wrinkles and folds to determine your treatment. JUVÉDERM injectable gel is available in two formulations—JUVÉDERM Ultra for versatility in contouring and volumizing facial wrinkles and folds, and JUVÉDERM Ultra Plus, a robust formulation for volumizing and correcting deeper folds and wrinkles. This allows your healthcare professional to better tailor treatment to your unique needs. They may even take pre-treatment photographs so you can see the difference after treatment!

Before the procedure: Although anesthesia is not required, your healthcare professional may use topical or injectable anesthesia to numb the treatment area first.

The procedure: Your healthcare professional will ease the JUVÉDERM injectable gel under your skin to augment, or fill, wrinkles and folds. Following the injection, your healthcare professional may gently massage the treated areas. The procedure is quick and easy. The injection itself usually takes only about 15 minutes.

After the procedure: With JUVÉDERM, there is minimal recovery or downtime.

For the first 24 hours following treatment, you should avoid strenuous exercise, excessive sun or heat exposure, and consumption of alcoholic beverages in order to help minimize the risks of temporary redness, swelling, and/or itching at the treatment sites. After the treatment, some temporary injection-related reactions may occur, including redness, pain, firmness, swelling, and bumps. Studies have shown that these are usually mild to moderate in nature and clear up on their own in 7 days or less. If you experience swelling at the injection site, you can apply an ice pack for a brief period. Your healthcare professional will tell you when makeup may be applied after your treatment.

Seeing results: You should see an immediate improvement in the treatment areas. Most patients need one treatment to achieve optimal wrinkle smoothing. And one treatment could smooth your lines and wrinkles for up to 1 year! However, results may vary and correction is temporary. Supplemental “touch up” treatments may be required to achieve and maintain optimal results.

Frequently Asked Questions

What is JUVÉDERM?

JUVÉDERM is the only HA filller with FDA approval to last up to one year.* Ask your physician how you can get long-lasting results with JUVÉDERM. JUVÉDERM injectable gel is a “next-generation” smooth consistency gel dermal filler that helps to instantly restore your skin's volume and smooth away facial wrinkles and folds like your “smile lines” or “parentheses” (nasolabial folds—the creases that run from the bottom of your nose to the corners of your mouth). JUVÉDERM comes in two formulations—JUVÉDERM Ultra and JUVÉDERM Ultra Plus.

JUVÉDERM is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

What does JUVÉDERM do?

JUVÉDERM injectable gel temporarily adds volume to facial tissue and restores a smoother appearance to the face.

What is JUVÉDERM indicated for?

JUVÉDERM Ultra and JUVÉDERM Ultra Plus injectable gels are indicated for injection into the mid to deep dermis (below the outer layer of skin) for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases running from the bottom of your nose to the corners of your mouth, aka smile lines or parentheses).

Why does JUVÉDERM come in two formulations?

JUVÉDERM injectable gel is available in two formulations to allow your healthcare professional to tailor treatment to your unique needs. JUVÉDERM Ultra provides versatility in contouring and volumizing facial wrinkles and folds. JUVÉDERM Ultra Plus is a more robust formulation for volumizing and correcting deeper folds and wrinkles.

What makes JUVÉDERM different from other dermal fillers?

JUVÉDERM is the ONLY hyaluronic acid (HA) filler FDA approved to last up to 1 year.* Our unique manufacturing process provides a high concentration of cross-linked hyaluronic acid for long-lasting results. It also works to create a smooth consistency gel that flows easily into the skin and provides a smooth, natural look and feel. All other hyaluronic acid dermal fillers currently on the market are made of granular consistency gels. And, JUVÉDERM is the first hyaluronic acid dermal filler that has demonstrated its safety and effectiveness in persons of color.

JUVÉDERM is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

What is hyaluronic acid?

Hyaluronic acid is a naturally occurring substance found in all mammals that helps to hydrate and add volume to your skin. In addition to its use as an aesthetic treatment, hyaluronic acid has also been used for more than 20 years for injection into arthritic joints to aid movement as well as for eye surgeries and wound repair.

What is cross-linked hyaluronic acid?

“Uncross-linked” hyaluronic acid in its natural form is in a liquid state. “Cross-linking” is the process through which hyaluronic acid is made into a gel product that can be injected into the skin for long-lasting results.

How is JUVÉDERM injectable gel used in treatment?

Your healthcare provider eases JUVÉDERM injectable gel into the skin using a fine needle to temporarily fill in and augment the treatment area and smooth moderate to severe facial wrinkles and folds such as “smile lines” or “parentheses” (nasolabial folds) and “marionette lines” (oral commissures). JUVÉDERM temporarily adds volume to the skin and may give the appearance of a smoother surface.

What will treatment with JUVÉDERM injectable gel accomplish?

JUVÉDERM injectable gel will help to smooth moderate to severe facial wrinkles and folds. Most patients need one treatment to achieve optimal wrinkle smoothing. And one treatment could smooth your lines and wrinkles for up to 1 year. Ask your doctor what you should expect from your initial treatment and when they would recommend rescheduling another appointment.

Is treatment with JUVÉDERM injectable gel painful?

Injections may cause some discomfort during and after the injection. The smooth consistency gel of JUVÉDERM allows your doctor to administer it easily and smoothly. And, JUVÉDERM is injected directly into the skin using a fine needle to reduce injection discomfort. Your doctor may choose to numb (anesthetize) the treatment area to further minimize discomfort.

How long does treatment usually take?

The injection process takes only about 15 minutes. You'll also need to allow time to consult with your doctor prior to treatment.

What kind of doctor can provide treatment with JUVÉDERM injectable gel?

Any authorized healthcare professional can administer JUVÉDERM injectable gel, but dermatologists, plastic surgeons, ophthalmologists, otolaryngologists (ear, nose, and throat doctors), or physicians specializing in cosmetic procedures are generally more experienced.

Does the correction last forever?

No. Correction is temporary; therefore, touch-up injections as well as repeat injections are usually needed to maintain optimal corrections.

How long do results last?

JUVÉDERM is the ONLY hyaluronic acid (HA) filler FDA approved to last up to 1 year.

JUVÉDERM is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

What are the possible side effects of JUVÉDERM injectable gel?

Most side effects are mild or moderate in nature, and their duration is short lasting (7 days or less). The most common side effects include, but are not limited to, temporary injections site reactions such as redness, pain/tenderness, firmness, swelling, lumps/bumps, bruising, itching, and discoloration. As with all skin injection procedures there is a risk of infection.

Can people with different skin tones/colors be treated with JUVÉDERM?

Yes. In fact, JUVÉDERM injectable gel is the first FDA-approved hyaluronic acid dermal filler that has proven its safety and effectiveness in persons of color. Studies with JUVÉDERM showed no increased risk of hyperpigmentation or hypertrophic scarring in patients of color.


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