Estyme is an innovative range of hyaluronic acid dermal fillers designed to restore lost facial volume, soften wrinkles and enhance facial contours while maintaining a natural-looking appearance. Developed using advanced COLD-X technology, Estyme offers specialised formulations for treating the cheeks, lips, nasolabial folds and lines around the mouth. Whether you are looking to address visible signs of ageing or subtly enhance your facial features, Estyme provides a personalised approach to facial rejuvenation without surgery.
At London Medical and Aesthetic Clinic in Marylebone, Estyme treatments are performed by Dr Ayham Al-Ayoubi, a leading facial plastic surgeon with more than 20 years of experience in aesthetic medicine, facial rejuvenation and advanced injectable treatments. Drawing on his extensive knowledge of facial anatomy, proportions and the ageing process, Dr Al-Ayoubi carefully plans each treatment to complement your natural features, restore facial balance and achieve refined, natural-looking results.
Estyme uses hyaluronic acid, a substance naturally present in the skin that helps maintain hydration, volume and structural support. When injected into carefully selected areas, the filler can replenish lost volume, smooth facial folds and improve definition. Unlike anti-wrinkle injections, which temporarily reduce muscle activity, Estyme addresses changes in facial volume and tissue support.
The Estyme range includes several formulations with different properties, allowing Dr Al-Ayoubi to tailor treatment to your facial anatomy, skin condition and aesthetic goals. From subtle lip enhancement to restoring cheek volume and softening deeper facial folds, the emphasis is on achieving balanced results that enhance your appearance without unnecessarily changing your natural facial characteristics.
What Is Estyme?
Estyme is an innovative range of injectable hyaluronic acid dermal fillers designed to restore facial volume, soften wrinkles and enhance natural facial contours. Hyaluronic acid is a substance naturally present in the skin and connective tissues, where it plays an important role in maintaining hydration, elasticity and structural support.
As we age, the face undergoes gradual changes in collagen production, skin elasticity, fat distribution and underlying bone structure. These changes can contribute to a loss of fullness in the cheeks, deeper folds around the nose and mouth, reduced lip definition and alterations in overall facial proportions.
Estyme offers a non-surgical approach to addressing these concerns by replenishing volume and providing support within targeted facial tissues. Depending on the formulation, treatment can help restore cheek contours, soften nasolabial folds, improve lines around the mouth and enhance lip volume and definition.
Developed by SYMATESE, a French company specialising in medical biomaterials and injectable technologies, Estyme incorporates proprietary COLD-X technology. This manufacturing process uses lower temperatures during the cross-linking of hyaluronic acid, with the aim of preserving its molecular structure while creating a stable injectable gel.
The Estyme range includes four specialised formulations — Smooth, Form, Lips and Sculpt — each developed with different properties to address specific facial concerns. This allows Dr Ayham Al-Ayoubi to select an appropriate formulation based on your facial anatomy, degree of volume loss, skin characteristics and desired treatment outcome.
How Does Estyme Work?
Estyme works by introducing a specially formulated hyaluronic acid gel into carefully selected layers of facial tissue, where it provides volume, support and improved contour definition. The treatment addresses changes in facial structure associated with ageing or naturally occurring differences in facial proportions.
Hyaluronic acid has a natural ability to bind water, helping maintain hydration and tissue volume. In Estyme dermal fillers, the hyaluronic acid undergoes a process called cross-linking, which creates a more stable gel that remains within the tissues for longer than naturally occurring hyaluronic acid.
Estyme uses SYMATESE’s proprietary COLD-X technology, which involves cross-linking hyaluronic acid at lower temperatures. According to the manufacturer, this process is designed to preserve more of the original hyaluronic acid chain structure during production while producing gels with different physical characteristics.
These characteristics influence how each formulation behaves within the tissues. Softer formulations are designed for areas requiring subtle correction and flexibility, such as the lips and lines around the mouth, while formulations intended for volume restoration provide greater structural support in areas such as the cheeks.
Once injected, the hyaluronic acid gel occupies space within the treated tissues, helping to restore lost fullness, soften facial folds or enhance existing contours. Results are generally visible shortly after treatment, although temporary swelling can initially affect the appearance of the treated area.
Over time, the body gradually breaks down and absorbs the hyaluronic acid, meaning the results are temporary. The duration of improvement depends on the formulation used, treatment area, individual metabolism and other patient-specific factors.
Dr Al-Ayoubi carefully considers the appropriate injection depth, placement and amount of filler required to achieve balanced results that complement your natural facial features.
The Estyme Dermal Filler Range
Estyme offers four specialised hyaluronic acid dermal filler formulations — Smooth, Form, Lips and Sculpt — each developed to address different facial concerns. From softening wrinkles and restoring lost volume to enhancing lip definition and cheek contours, the range allows treatment to be tailored to your individual facial anatomy and aesthetic goals.
Dr Ayham Al-Ayoubi will assess your facial proportions, skin quality and the areas you would like to improve before recommending the most appropriate Estyme formulation.
Estyme Smooth – Facial Lines and Wrinkles
Estyme Smooth is designed to soften the appearance of facial lines, particularly nasolabial folds and perioral wrinkles around the mouth. These lines can develop as the skin gradually loses collagen and elasticity, while repeated facial movements contribute to creases becoming more pronounced.
The formulation provides targeted hyaluronic acid support within the treated tissues, helping to smooth selected wrinkles and improve the appearance of the surrounding skin. It can be particularly useful where subtle correction is required without adding unnecessary facial volume.
Estyme Smooth may be suitable for patients concerned about visible lines around the nose and mouth who want to achieve a smoother, more refreshed appearance while preserving their natural facial expressions.
Dr Al-Ayoubi will assess the depth and underlying cause of your wrinkles to determine whether Estyme Smooth is appropriate and what degree of improvement can realistically be achieved.
Estyme Form – Nasolabial Fold Correction
Estyme Form is developed to improve moderate to pronounced nasolabial folds, the creases that extend from either side of the nose towards the corners of the mouth. These folds can deepen with age as facial fat distribution changes, skin elasticity decreases and the tissues around the mid-face gradually lose support.
By introducing hyaluronic acid into carefully selected tissue layers, Estyme Form helps restore volume and soften the appearance of these folds. Treatment can improve the transition between the cheeks and lower face, creating smoother facial contours without unnecessarily changing your natural features.
Estyme Form may be appropriate for patients whose nasolabial folds have become more noticeable with age or who naturally have deeper facial creases in this area.
Dr Al-Ayoubi considers the depth of the folds, surrounding cheek volume and overall facial proportions before planning treatment. Where volume loss in the cheeks contributes to pronounced folds, he may recommend assessing the mid-face as part of a broader facial rejuvenation approach.
Estyme Lips – Lip Enhancement and Definition
Estyme Lips is specifically formulated to enhance lip volume, shape and definition while maintaining a soft, natural-looking appearance. It can be used to address age-related loss of lip fullness, improve the definition of the lip borders or provide subtle enhancement for patients who would like fuller, more balanced lips.
As we age, the lips may gradually lose volume and definition, while fine lines and changes in the surrounding tissues can affect their appearance. Some patients may also have naturally thin lips or minor differences in symmetry that they would like to improve.
Estyme Lips introduces hyaluronic acid into selected areas of the lips to enhance fullness, refine contours and improve overall lip proportions. Treatment can be tailored to achieve subtle definition or a more noticeable increase in volume, depending on your anatomy and preferences.
Dr Al-Ayoubi carefully considers the relationship between the upper and lower lips, the shape of the Cupid’s bow, the lip borders and the surrounding facial features when planning treatment.
His approach focuses on achieving proportionate, balanced enhancement that complements your natural appearance, avoiding excessive volume or an overfilled result.
Estyme Sculpt – Cheek Volume Restoration and Contouring
Estyme Sculpt is developed to restore lost volume in the cheeks and mid-face, helping to improve facial contours and provide structural support where age-related changes have reduced fullness and definition.
As we age, changes in facial fat compartments, bone structure and skin elasticity can cause the cheeks to lose projection and appear flatter. This reduction in mid-face volume may also contribute to more pronounced nasolabial folds and changes in the overall balance of the face.
Estyme Sculpt provides targeted hyaluronic acid support within the appropriate tissue layers, helping to replenish lost cheek volume, enhance contour definition and restore a fuller appearance to the mid-face.
Treatment may be suitable for patients experiencing age-related cheek volume loss or those seeking subtle enhancement of their natural cheek contours without undergoing surgery.
Dr Al-Ayoubi will assess the distribution of facial volume, cheek projection, skin quality and the relationship between the mid-face and surrounding structures before recommending treatment.
The aim is to restore balanced facial proportions and achieve a refreshed, natural-looking appearance without creating excessive fullness or unnecessarily altering your facial characteristics.
What Is COLD-X Technology and How Is Estyme Different?
One of the distinguishing features of Estyme is its proprietary COLD-X technology, developed by SYMATESE to produce hyaluronic acid dermal fillers with specific physical characteristics for different facial treatment areas.
Hyaluronic acid naturally occurs in the skin but is gradually broken down by the body. To create longer-lasting injectable fillers, manufacturers use a process called cross-linking, which connects hyaluronic acid chains to form a more stable gel that can provide volume and support within the tissues.
COLD-X uses a lower-temperature cross-linking process designed to preserve more of the original hyaluronic acid chain structure during manufacturing. According to SYMATESE, this approach helps minimise changes to the hyaluronic acid while allowing the production of gels with different levels of firmness, flexibility and structural support.
These properties are important because different areas of the face have different treatment requirements. For example, the lips require a formulation that accommodates natural movement, while restoring cheek volume generally requires a gel capable of providing greater structural support.
The Estyme range has therefore been developed with specialised formulations for different facial indications, allowing treatment to be tailored to the patient’s anatomy and aesthetic objectives.
Although COLD-X represents a distinctive manufacturing approach, it does not automatically mean Estyme is more effective, safer or longer-lasting than other hyaluronic acid fillers. The most appropriate product depends on the treatment area, facial anatomy, clinical evidence and individual patient requirements.
Dr Ayham Al-Ayoubi will assess these factors during consultation to determine whether Estyme is suitable and which formulation may provide the most appropriate treatment approach.
What Happens During an Estyme Consultation and Treatment?
Your Estyme treatment begins with a detailed consultation with Dr Ayham Al-Ayoubi at London Medical and Aesthetic Clinic in Marylebone. Each stage, from your initial facial assessment to treatment and aftercare, is carefully planned around your individual concerns, facial anatomy and aesthetic goals.
1.Facial Assessment
Dr Al-Ayoubi will begin by discussing the areas you would like to improve and the results you hope to achieve. He will assess your facial proportions, skin quality, existing volume distribution and the appearance of your features both at rest and during facial movement.
He will also examine how different facial structures interact, including the relationship between the cheeks, lips and surrounding tissues, to understand the underlying causes of your concerns.
Your medical history, previous injectable treatments, current medications, allergies and any relevant health conditions will be reviewed to determine whether dermal filler treatment is appropriate.
2. Personalised Treatment Planning
If Estyme is suitable, Dr Al-Ayoubi will recommend the formulation best suited to your treatment area and aesthetic objectives.
He will explain the proposed injection sites, the amount of filler that may be required, the improvement you can realistically expect and any potential limitations or risks.
Your treatment plan will be designed to complement your existing facial features, restore balance where appropriate and avoid unnecessary volume or excessive correction.
3. Estyme Injections
The treatment area will be carefully cleansed and prepared before the filler is administered through precisely positioned injections.
The injection technique, depth and amount of filler will depend on the selected formulation, the area being treated and your individual facial anatomy. Dr Al-Ayoubi will carefully consider these factors to achieve the planned correction while minimising unnecessary tissue trauma.
You may experience mild pressure, stinging or temporary discomfort during the injections. Appropriate measures to manage discomfort will be discussed before treatment.
The procedure is generally performed during an outpatient appointment, although the time required varies according to the number and size of the areas being treated.
4. Aftercare and Follow-Up
Following treatment, Dr Al-Ayoubi will assess the treated areas and provide personalised aftercare instructions to support recovery and minimise the risk of complications.
Some temporary swelling, redness, tenderness or bruising may occur, particularly around the lips. These effects generally improve as the tissues recover.
A follow-up assessment may be recommended to review the results, address any concerns and determine whether further treatment would be appropriate.
When Will I See Estyme Results?
Estyme can produce a visible improvement in facial volume and contours shortly after treatment because the hyaluronic acid gel provides immediate support within the treated tissues. Changes in cheek fullness, lip shape or the appearance of facial folds may therefore be noticeable soon after injection.
However, the initial appearance may be influenced by temporary swelling, redness or bruising. These effects can be particularly noticeable following lip enhancement, where the tissues are more sensitive.
As swelling settles over the following days, the treated areas generally begin to look more refined, allowing the contours and degree of correction to become clearer. Some patients may require longer for swelling or bruising to resolve completely.
The degree of improvement depends on the Estyme formulation used, the amount of filler administered, the treatment area and your individual facial anatomy.
Dr Al-Ayoubi will explain what results may reasonably be expected during your consultation and advise when the outcome can be appropriately assessed.
How Long Does Estyme Last?
Estyme provides temporary facial enhancement, with the duration of results varying according to the formulation used, treatment area and individual patient factors.
Hyaluronic acid dermal fillers are gradually broken down by the body over time. The rate at which this occurs can differ between patients and may be influenced by individual metabolism, facial movement, the amount of filler administered and the characteristics of the treated tissues.
Areas subject to frequent movement, such as the lips, may respond differently from areas where filler is used to provide volume and structural support, such as the cheeks.
As the hyaluronic acid gradually breaks down, the treated areas may progressively return towards their previous appearance. Changes in facial ageing and tissue structure may also continue during this period.
During your consultation, Dr Al-Ayoubi can explain the expected longevity of the recommended Estyme formulation and advise whether maintenance treatment may be appropriate to preserve your desired results.
Estyme Recovery and Downtime
Estyme is a non-surgical injectable treatment that generally involves limited downtime. Many patients can return to their usual daily activities shortly after their appointment, although some temporary side effects should be expected.
Common reactions include swelling, redness, tenderness, bruising or mild discomfort around the injection sites. These effects are usually temporary and tend to improve as the treated tissues recover.
Swelling may be more noticeable following lip enhancement, while bruising can occasionally take longer to resolve, particularly in patients who are more prone to bruising.
The recovery experience varies depending on the treatment area, the amount of filler administered, the injection technique and your individual response.
Although most patients recover without significant problems, dermal fillers can occasionally cause complications, including infection, inflammatory reactions, nodules, asymmetry or unintended changes in facial contours.
Rarely, vascular complications can occur if filler obstructs blood circulation, potentially causing tissue damage or visual complications.
Dr Al-Ayoubi will explain the potential risks before treatment and provide instructions on recognising symptoms that require urgent medical attention.
Estyme Aftercare
Following Estyme treatment, appropriate aftercare can help minimise swelling, irritation and discomfort while the treated tissues recover.
Dr Al-Ayoubi will provide instructions tailored to your treatment, but general recommendations may include:
- Avoid unnecessary pressure: Do not rub, massage or apply excessive pressure to the treated areas unless specifically instructed by your clinician.
- Limit strenuous exercise: You may be advised to avoid intense physical activity temporarily, particularly if it increases swelling or discomfort.
- Avoid excessive heat: Saunas, steam rooms and prolonged exposure to high temperatures may need to be avoided while initial swelling settles.
- Be gentle with the treated skin: Avoid unnecessary manipulation of the injection sites and follow any advice regarding skincare or make-up application.
- Allow swelling to settle: Mild swelling, tenderness or bruising can occur after treatment. Do not attempt to reshape or reposition the filler yourself.
- Attend follow-up appointments: Where recommended, a follow-up assessment allows Dr Al-Ayoubi to review your results and address any concerns.
Most minor injection-site reactions improve naturally. However, increasing or severe pain, unusual skin discolouration, blanching, or skin that becomes dusky or mottled may indicate a circulation problem and require immediate medical assessment.
Any visual disturbance following dermal filler treatment is a medical emergency and requires immediate emergency care.
Is Estyme Safe?
Estyme is a range of hyaluronic acid dermal fillers developed for facial aesthetic treatments. Hyaluronic acid fillers are widely used in aesthetic medicine, but all injectable procedures carry potential risks, and no dermal filler treatment is completely free from complications.
The most common side effects are temporary and may include swelling, bruising, redness, tenderness or discomfort around the injection sites. These reactions generally improve as the treated tissues recover.
Less common complications include infection, inflammatory nodules, persistent swelling, asymmetry or unwanted filler placement.
A rare but serious complication is vascular occlusion, which occurs when filler obstructs blood flow within a blood vessel. This can result in tissue damage and, in exceptional circumstances, visual impairment or blindness. Immediate medical assessment is essential if symptoms suggest a vascular complication.
Estyme is not suitable for everyone. Factors that may prevent or require postponement of treatment include pregnancy, breastfeeding, relevant allergies, active infection or inflammation at the proposed injection site, and certain medical conditions or medications.
Particular consideration is required for patients with a history of reactions to injectable treatments, bleeding disorders, autoimmune conditions or medications that may affect treatment safety. The applicable product instructions must also be considered when determining suitability.
Before proceeding, Dr Ayham Al-Ayoubi will review your medical history, allergies, current medications and individual risk factors. He will explain the potential benefits, limitations and complications so that you can make an informed decision about treatment.
Who Is Suitable for Estyme?
Estyme may be suitable for adults seeking non-surgical improvement in facial volume, lip shape or selected facial wrinkles.
Depending on the formulation, treatment may be considered for patients who wish to:
- Restore lost volume and improve definition in the cheeks and mid-face.
- Soften moderate to pronounced nasolabial folds.
- Improve the appearance of selected lines around the mouth.
- Enhance lip volume, shape and definition.
- Address age-related changes in facial proportions and tissue support.
Estyme may also be appropriate for patients seeking subtle enhancement of their existing facial features rather than correction of age-related volume loss.
However, suitability depends on several factors, including facial anatomy, skin quality, medical history, previous treatments and individual aesthetic objectives.
Patients who are pregnant or breastfeeding, have an active infection at the proposed treatment site, or have certain allergies or medical conditions may not be suitable for treatment. Previous reactions to injectable products and medications that affect bleeding or immune function also require careful assessment.
During consultation, Dr Al-Ayoubi will evaluate your concerns, review any relevant medical factors and explain the results that may reasonably be achieved before determining whether Estyme is an appropriate treatment option.
Why Choose Dr Ayham Al-Ayoubi for Estyme Treatment?
Estyme treatments at London Medical and Aesthetic Clinic are performed by Dr Ayham Al-Ayoubi, a leading facial plastic surgeon with more than 20 years of experience in aesthetic medicine, facial rejuvenation and advanced injectable treatments.
Dr Al-Ayoubi combines extensive experience in facial aesthetics with a detailed understanding of facial anatomy, tissue structure and the changes that occur during ageing. This knowledge is particularly important when performing dermal filler treatments, where precise placement and appropriate product selection are essential for achieving balanced results.
Rather than focusing on individual wrinkles or areas of volume loss in isolation, he assesses the face as a whole, considering the relationship between the cheeks, lips, jawline and surrounding facial features. This allows treatment to be planned around your natural proportions and the underlying causes of your concerns.
Each Estyme treatment is tailored to your individual anatomy, skin characteristics and aesthetic goals, with careful consideration of the appropriate formulation, injection technique and amount of filler required.
His approach focuses on restoring facial harmony, enhancing natural contours and achieving subtle, refined results without unnecessary volume or an overfilled appearance.
Frequently Asked Questions
What is Estyme used for?
Estyme is a range of hyaluronic acid dermal fillers designed to restore lost facial volume, soften selected wrinkles and enhance facial contours without surgery. It can be used to improve the appearance of nasolabial folds, lines around the mouth, cheek volume loss and lip shape or fullness.
At London Medical and Aesthetic Clinic, Dr Ayham Al-Ayoubi will assess your facial anatomy and recommend the most suitable formulation to address your concerns while maintaining a natural-looking appearance.
What makes Estyme different from other dermal fillers?
Estyme incorporates COLD-X technology, a proprietary manufacturing process developed by SYMATESE that uses lower temperatures during hyaluronic acid cross-linking. According to the manufacturer, this process is designed to help preserve the structure of the hyaluronic acid during production.
The range also includes specialised formulations for different facial areas, allowing treatment to be tailored to your individual needs. However, no single filler is necessarily the best option for everyone. Dr Al-Ayoubi will consider your facial anatomy, skin quality and aesthetic goals before recommending treatment.
Which Estyme filler is best for me?
The most appropriate Estyme formulation depends on the area you would like to improve and the results you hope to achieve.
Estyme Smooth is designed for selected facial lines, including nasolabial folds and wrinkles around the mouth. Estyme Form targets nasolabial folds, Estyme Lips is intended for lip enhancement, and Estyme Sculpt is designed to restore cheek volume.
During your consultation, Dr Al-Ayoubi will assess your facial proportions, degree of volume loss and treatment objectives to determine which formulation may be most suitable.
Can Estyme restore lost cheek volume?
Yes. Estyme Sculpt is designed to address volume loss in the cheeks and mid-face, which can occur as part of the natural ageing process. By providing support within the treated tissues, it can help restore cheek fullness, improve contour definition and create a more balanced facial appearance.
Dr Al-Ayoubi will assess your existing cheek structure, skin quality and the extent of volume loss before recommending the appropriate amount and placement of filler. The aim is to achieve a refreshed appearance without creating excessive fullness.
Can Estyme enhance my lips without making them look overfilled?
Yes. Estyme Lips can be used to enhance lip volume, improve definition and refine lip shape, with treatment tailored to your natural proportions and preferences.
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