We pride ourselves to be the very first clinic to introduce the revolutionary dermal filler – Ellanse into the UK by Dr Ayham Al-Ayoubi in 2010. One year later, he pioneered this revolutionary dermal filler worldwide.
Ellanse is the first and the only Dermal Filler which acts as a biostimulator of collagen with the results lasting up to two to five years.
Ellanse developed by AQTIS Medica, is the first dermal filler which offers a safe unique tunable longevity, specifically designed for the field of aesthetic medicine and surgery with the results lasting from three to five years.
Ellanse is a non-animal, non-bacterial and non-human derived product. It is a natural bio-simulator, since it stimulates the creation of patient own new collagen.
Ellanse is made of Poly-Caprolactone and is a well-known totally bioresorbable soft medical polymer. ELLANSE offers the maximum potential for modeling due to the combination of optimum viscosity, unique elasticity and uniform homogeneity,
Ellanse uses
ELLANSE offers the maximum potential for modeling due to the combination of optimum viscosity, unique elasticity and uniform homogeneity, hence, the ELLANSE family can be used in a variety of beautifying indications:
- Correcting wrinkles and folds
- Volumizing
- Contouring
- Sculpting
The ELLANSE is an injectable filler indicated for deep dermal and subdermal implantation. The nasolabial folds used in clinical studies are representative for deep and sub-dermal soft tissue augmentation of the facial area.
Ellansé is a dermal filler providing immediate results, as well as, Bio-stimulation inducing neo-collagenesis for longer-lasting and sustained results.
Due to the optimum viscosity and elasticity of the gel-carrier, the wrinkles and folds undergo immediate physical correction after treatment.
The gel-carrier is gradually resorbed over a period of several weeks after treatment.
Ellanse Suitability
Ellanse is suitable for both woman and men of different ages. It can help with deep folds around the mouth and nose, sunken cheeks, facial scars, deep acne scars and loose skin. It has optimal bio-compatibility, due to the very smooth spherical micro-spheres. It is predictable, controlled and has tunable bioresorption, with an excellent safety profile. Unique tunable longevity options for personalized and tailored treatment.
Ellanse is ideal for long lasting lines and wrinkle correction and enhances cheek volume and stimulates collagen in a natural way.
Ellanse is ideal for restoring facial contours and volume and correcting facial laxity, improving the jaw line and other areas.
Patients can achieve full face lifting without the need of aggressive surgery, with the result lasting up to three to four years.
 Ellanse Treatment
The procedure for Ellanse injection is very quick, often lasting just ten to fifteen minutes. Many patients experience no pain at all or minimum discomfort. There is no recovery time needed, patients can resume their normal activities right after the treatment.
Ellanse is gently injected into the required area and hydrate the skin. It also has antioxidant qualities which provide instantly smoother skin. The results last between 1- 4 years.
Immediate side effects are very rare and may include injection-related events, at the site of injection, such as, minimum redness, slight tenderness or discomfort, some bruising or rarely swelling.
Delayed appearance of small bumps under the skin in the treated area could rarely occur. Generally these bumps are not visible and may only be noticed when pressing on the treated area. All of these side effects usually last only a day or two.
The specifically designed microsphere characteristics provide a safe and long-lasting high quality scaffold for tissue infiltration.
Ellanse Saftey
Ellanse is officially approved by MHRA in the UK and the FDA in The USAÂ for restoration and correction of the signs of facial fat loss and is used for treating facial lines and wrinkles.
In capable doctor hands, with the right training and experience, this is a very safe and effective procedure. Over time the technique has evolved to optimize the effects and reduce problems.
The mechanism consists of sustained performance and complete bioresorption.
The excellent performance and safety of the Ellanse is well grounded in its mode of action and specifically tunable characteristics.
Patient satisfaction at twelve months evaluated on the basis of GAIS (Global Aesthetic Improvement Scale) for Ellanse was found to be 90%. Average physician evaluation shows improvement in 92% patients based on GAIS.
Ellanse treatments were rated to be excellent or good by 90% of patients on the scale of likelihood to return for repeat treatment at twelve months.
Ellanse Vs Dermal Fillers
Over the course of time, our skin gradually loses its natural collagen, leading to facial laxity and the formation of wrinkles and folds. Ellanse uses the body’s natural response to stimulate the generation of the body’s own collagen (neo-collagenesis) – restoring a fresh, youthful look.
Ellanse is different from other fillers, as it gives the desired beautiful aesthetic result that lasts longer than conventional dermal fillers.The unique advantages of Ellanse are sustained performance, tunable longevity and total bioresorbability.
Ellanse also offers the advantage over other fillers, as it allows immediate correction and sustained performance from one up to four years.
Ellanse at LMA clinic
Patients travel from all over the UK and from around the world to have Dr Ayham Al-Ayoubi perform Ellanse treatments at the London Medical and Aesthetic Clinic, which is one of the leading training centers for Ellanse treatment in the UK and Europe.
Dr Ayham Al-Ayoubi the very first facial plastic surgeon to introduce and poineer Ellanse into the UK in 2010. One year later, he pioneered this revolutionary dermal filler worldwide.
Ellanse FAQ’s
The answer to some of the most common questions patients may have about Ellanse treatment.
It’s common for patients to have questions about the aesthetic and laser treatments and at the London Medical and Aesthetic Clinic, it is essential for us that all our patients should feel confident, knowledgeable and comfortable at every stage of their journey of their treatments at our clinic.
To help our patients finding the answers they need, here are a few of the most common questions that we find our patients frequently asked:
What is Ellanse?
Ellanse is a non-hyaluronic acid filler and it is made of Polycaprolactone Microspheres that are fully bioresorbable, It is injected into the skin to lift, sculpt and restore lost volume.
Ellanse is a non-animal, non-bacterial and non-human derived product. It is a natural bio-simulator, since it stimulates the creation of patient own new collagen.
What areas of the face can be treated with Ellanse?
Ellanse is highly versatile and suitable for treating various areas affected by aging or volume loss. These include:
• Cheeks: To restore mid-face volume and lift sagging skin
• Temples: To correct hollowing and improve facial balance
• Nasolabial folds: To soften deep smile lines
• Marionette lines: To reduce shadows around the mouth
• Jawline and chin: To sculpt and define facial contours
Important note: Ellanse is not suitable for lip augmentation, as the product is too firm and not reversible, making it unsuitable for the soft and mobile nature of lips.
Is Ellansé safe?
Yes, Ellansé is considered very safe when administered by an experienced facial plastic surgeon or cosmetic doctor. It carries CE-mark certification in Europe and is FDA-approved in the US for specific indications, reflecting its compliance with rigorous safety and quality standards.
Most side effects tend to be mild and temporary, typically including redness, slight swelling, tenderness, or bruising at the injection site, which usually resolve within a few days. In rare cases, small nodules or bumps may develop under the skin; however, these are generally manageable and tend to diminish over time.
Also, EllansĂ© is made of Polycaprolactone Microspheres that are fully bioresorbable, meaning the product naturally breaks down within the body over time without leaving any permanent foreign material. This bioresorbable, combined with it’s collagen-stimulating properties, contributes to a safe profile and natural-looking results.
What is Ellanse used for?
Ellanse offers the maximum potential for modelling due to the combination of optimum viscosity, unique elasticity and uniform homogeneity, hence, the ELLANSE family can be used in a variety of beautifying indications: Correcting wrinkles and folds, volumizing, contouring and sculpting.
What is Ellanse filler?
Ellanse is a unique dermal filler that works by correcting the wrinkles and folds in the skin, but also by stimulating the body’s own natural collagen to have a long lasting, natural result. It is a semi-permanent filler.
Who is Ellanse Suitable for?
Ellanse is suitable for both woman and men of different adult age group. It can help with deep folds around the mouth and nose, sunken cheeks, facial scars, deep acne scars and loose skin. It has optimal bio-compatibility, due to the very smooth spherical micro-spheres. It is predictable, controlled and has tuneable bio absorption, with an excellent safety profile. Unique tuneable longevity options for personalized and tailored treatment.
How soon will I see results of Ellanse Treatment?
Immediate improvement is visible right after treatment due to the gel carrier’s volumizing effect. Over the following 3-6 months, the collagen-stimulating effects develop gradually, enhancing skin firmness, texture, and volume. Ellanse results continue to improve during this period and can last several years depending on the product used and individual patient factors.
How long does it Ellanse last for?
The results last between 1- 4 years. Nevertheless, each patient is different, nevertheless every patient is very individual and the results could vary from one patient to another.
What is the different between Ellanse & Hyaluronic Acid?
HA filler and Ellanse can be used to treat many of the same areas however they work in different ways so it is important to establish what you are looking to achieve. Both HA filler and Ellanse are great products to address lines on the face, they are ideal for Naso-labial folds and for a non-surgical nose job (Rhinoplasty).
Ellanse is ideal for long lasting lines and wrinkle correction and enhances cheek volume and stimulates collagen in a natural way. Ellanse is ideal for restoring facial contours and volume and correcting facial laxity, improving the jaw line and other areas. However, Ellanse should not be used under eyes or for lips augmentation.
Another major difference is longevity. HA fillers tend to last between 6 to 18 months, depending on the product used and area treated. Ellanse offers versions that last up to 2- 4 years.
How does Ellansé stimulate collagen production?
Mr Ayham Al-Ayoubi explains: Ellansé contains Polycaprolactone Microspheres (PCL microspheres), which act as a scaffold for patient own body’s fibroblasts (collagen-producing cells). Once injected, these microspheres remain in place as the CMC gel carrier is gradually absorbed over several weeks. The body recognizes the microspheres as biocompatible materials and responds by building collagen around them.
This collagen synthesis is a gradual biological process that results in firmer, smoother skin over time. The newly formed collagen remains in the skin even after the PCL microspheres biodegrade, which is why the aesthetic results of Ellansé last far longer than traditional fillers.
Can Ellansé be combined with other treatments?
Yes, Ellansé is often part of a comprehensive anti-aging or facial rejuvenation treatment plan and can be combined safely with many other aesthetic procedures, such as:
- Botulinum toxin to relax dynamic wrinkles
- Hyaluronic acid fillers for areas where reversibility or softness is preferred (e.g. lips, tear troughs)
- Thread lifts for additional tissue lifting
- Microneedling or RF Microneedling for texture and skin tightening
- Laser treatments or chemical peels (typically done before or weeks after Ellansé)
Can Ellanse be reversed?
Ellanse, like Hyaluronic Acid, can be dissolved. However, the cosmetic doctor must be very careful, accurate and safe to avoid any long-term complications. Also, it extremely important to have realistic expectations, choose a reputable plastic surgeon or cosmetic doctor, who should starts with a conservative amount. Furthermore, If any issues arise, they typically need to be managed with massage, steroid injections, or in rare cases surgical removal.
Is Ellanse FDA approved?
Yes, as Polycaprolactone (PCL; Ellanse, AQTIS Medical) filler available on the US market and the PCL product is FDA approved for many years in a suture and as a drug delivery system. Also, It carries CE-mark certification in Europe, all reflecting its compliance with rigorous safety and quality standards.
Can Ellanse help with skin laxity?
Yes, while Ellansé is primarily a volume-restoring and collagen-stimulating filler, the new collagen generated improves skin firmness and elasticity, which helps reduce mild to moderate skin laxity.
For severe sagging or loose skin, Ellansé is usually combined with other treatments like thread lifts, ultrasound, or radiofrequency skin tightening procedures for best results.
Will combining Sculptra and Ellansé make the results last longer?
Yes, because both stimulate collagen but in slightly different ways and durations. Ellansé provides immediate volume and long-lasting collagen support (up to 2- 4 years depending on type), while Sculptra’s collagen stimulation is more gradual and may complement the effect.
Can Ellanse be used to treat nasolabial folds?
Yes, Ellanse is very effective for treating nasolabial folds, which are the lines that run from the sides of the nose to the corners of the mouth. Over time, these folds deepen due to volume loss and skin laxity.
Ellanse restores volume by replacing the lost subcutaneous tissue and stimulating collagen production in the area, which smooths out the folds and improves facial contours.
Because of its ability to provide structural support, Ellanse can soften deep folds with a natural appearance that lasts longer than many traditional fillers. However, precise injection technique is critical in this area to avoid lumpiness or overcorrection.
How does Ellanse affect the aging process?
Aging is characterized by progressive loss of collagen, elastin, and fat in the skin, leading to wrinkles, sagging, and volume loss. Ellanse helps slow down the visible signs of aging by directly addressing collagen depletion. By stimulating your body’s own collagen production.
Ellanse restores the skin’s natural support structure, improving thickness, firmness, and elasticity. Unlike temporary fillers that simply “fill in” wrinkles, Ellansé promotes a biological rejuvenation process, which not only improves volume but also enhances overall skin quality.
This means the skin becomes more resilient, hydrated, and youthful over a longer period. The treatment essentially helps patients “age more gracefully” by supporting the skin’s natural regenerative abilities.
Are there any medications or supplements I should avoid before or after Ellanse?
Before Ellansé treatment, it is generally recommended to avoid medications and supplements that can increase bleeding or bruising risk. These include Aspirin, Nonsteroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen, Vitamin E, Fish oil, Garlic supplements, and Certain herbal products such as ginkgo biloba or St. John’s Wort. Avoiding these for about one week prior to treatment can minimize bruising and swelling.
After treatment, it is advisable to avoid anti-inflammatory medications for a few days because inflammation is part of the natural collagen-stimulating process.
Can Ellanse help with acne scars or skin texture?
While Ellanse is not specifically designed as a scar treatment, its collagen-stimulating properties can improve mild skin texture irregularities by thickening the dermis and improving skin elasticity. This can lead to a subtle smoothing effect on superficial acne scars or creepy skin.
For deeper or more severe scars, Ellanse is often combined with other treatments such as Microneedling, CO2 laser resurfacing, or chemical peels to achieve better overall skin quality improvements.
Why Should I Go to Mr Ayham Al-Ayoubi for Ellanse ?
Mr Ayham Al-Ayoubi is internationally recognised for his extensive experience with Ellanse, a collagen-stimulating dermal filler. He was reportedly the first facial plastic surgeon to introduce Ellanse to the UK in 2010, and since then, he has performed over 2,000 Ellanse procedures at his London Medical and Aesthetic Clinic.
Beyond his pioneering work in the UK, Mr Al-Ayoubi has played a major role in introducing Ellanse internationally, including Japan, Russia, Ukraine, Hungary, Portugal, Saudi Arabia, the UAE, and many other countries. His global contribution has helped establish Ellanse as a trusted and effective treatment for natural facial rejuvenation.
As a leading Ellanse training surgeon and internationally recognised expert, Mr Al-Ayoubi is regularly invited to speak at national and international conferences and congresses, where he delivers expert lectures and leads Ellanse masterclasses for medical professionals.
Mr Al-Ayoubi’s treatment philosophy focuses on enhancing natural facial beauty rather than creating an overfilled or artificial appearance. He emphasises Ellansé’s unique ability to stimulate the body’s own collagen production, restoring a youthful, natural-looking glow.
In his clinical practice, he often combines Ellanse with complementary treatments such as Sculptra to achieve a comprehensive and long-lasting “injectable facelift” effect. Every procedure is preceded by a thorough clinical assessment, which includes detailed evaluation of the patient’s medical history, facial anatomy, skin quality, and aesthetic goals — ensuring a fully personalised treatment plan tailored to each individual.
